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sulaco

05/14/13 4:11 PM

#122242 RE: pphmtoolong #122227

PPHM2Long, BAVI is most definitely an immune-booster


because by neutralizing PS-mediated immunosuppression, the adaptive immune response is reactivated.

That means CD4 null cells will differentiate into the Th1 arm and crank out more cytokines, IL-2, NKs, and macrophages to go after the tumor and its vasculature.

The cancer microenviroment promotes PS extroversion which is inarguably a powerful immunosuppresant. Bavi fires the immune system back up by "masking" the extroverted PS signal.

Now, you're right, as an imaging agent, Bavi can reveal cancer cells with extroverted PS by lighting them up like a Christmas tree. There's all kinds of potential applications for this dimension of Bavi.

All the best,

Joe