Yes, many cases of drugs working in lab animals but not humans. Lots of drugs fail in Phase 2 because of that. However, I don't think that will be the case here since Kevetrin was effective against human xenografts on mice, and not mice given a disease or cancer.
yes, rezulin. i am a diabetic and used it. came on with great fanfare, lasted a year and was pulled because it cause 54 people that year to die from liver failure.