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Replies to post #153064 on Biotech Values

Replies to #153064 on Biotech Values
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DewDiligence

11/27/12 4:58 PM

#153067 RE: ciotera #153064

IFN intolerant in my interpretation simply means having experienced IFN previously and not having tolerated it well…

That’s what the term ought to mean, literally, but that’s not how GILD defined the admissible patient pool for the POSITRON study.
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oc631

11/27/12 11:36 PM

#153126 RE: ciotera #153064

IFN intolerant in my interpretation simply means having experienced IFN previously and not having tolerated it well - this has little to do with one's IL28b status.





I agree. Furthermore Pharmasset viewed IL28b status in interferon-free therapy as being irrelevant. Patients continued to be stratified under this measure simply to appease the change-adverse mindset at the FDA.