I'm not a "doubter" of RNAi utility. I do however have a healthy scepticism regarding the specificity of RNAi, which is often assumed (incorrectly) to be nearly perfect.
I suspect your concern is understated from your own statements and links but my interest is not exactly theoretical.
Got some purty mouse pictures that perhaps not everyone will be able to see without a recent version of Explorer. They take a while to load:
This and much more pre-clinical work by SNT in various indications presage marvels untold with SNT's Death Switch.
The problem is that all depends on RNAi for now (as opposed to the gene therapy that appears to have been abandoned).
Varied plant species from trees to yeast have demonstrated resistance to disease and parasites, among other things, with SNT's gene discovery but "natural" breeding or bioengineering produces superior plants
The rather recent discovery that the genes exist in animals, naturally including man, is mighty fine for those unborn (or more precisely unconceived) but not so fine for those of us with inferior genes. :-)
Market Data 
Markets 
AI
