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jq1234

09/30/12 12:36 AM

#149662 RE: iwfal #149660

MetMab Met high and low population were based on all NSCLC, both squamous and non squamous. They never reported result from sub population of squamous and non squamous. We already had this discussion before that literature showed majority squamous don't have Met expression at all, thus Met inhibitor should produce negative result for this population. This is consistent with ARQL ph2 result from squamous population. ARQL excluded squamous from ph3.