Replies to post #89754 on Avid Bioservices Inc (CDMO)

[DrRocker]

CJ,
I believe Dew's contention is that because Peregrine did not report that the results achieved statistical significance the ORR numbers are of no consequence and thus failed to meet the primary endpoint. He is reaching here and loves to come on the board with his fly by negative spins to provoke the group.Could this be payback for all the challening messages our group has posted on the Biotech Values board? Regardless, it would seem to be better to ignore his clearly biased provocations to avoid giving him the satisfaction of stoking our ire.
Big week coming up with news that should drown out the noise from the peanut gallery naysayers
Rocker

[exwannabe]

But, for some reason Bavi/3mg at ORR=17.9% (double+) is “failing to meet its primary endpoint” to you**?

Because or the size of the trial, the Bavi ORR data has a P value of about .3 (for the high dose arm, higher for the low dose arm).

The Tarceva trial does not list the P value, but it lists the 95% confidence intervals which do not overlap, so it is p<.05

I know that P values mean nothing to you guys, but they mean a lot with the FDA. And that is not an opinion.