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biomaven0

09/02/12 9:48 PM

#148095 RE: mcbio #148084

Phase 2 results OGXI reported at ASCO this year for OGX-427



I think they are likely much too late to the party as monotherapy. For combo therapy in patients refractory to Xtandi/Zytiga (where the expense would be a real issue), I suppose it might be interesting, but so would other combinations (like a PI3k inhibitor).

For that matter the Exelixis drug shows pretty decent activity in patients that have failed Xtandi/Zytiga.

Peter