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JohnWayne

08/24/12 9:55 AM

#147652 RE: acgood #147606

perifosine at ASCO...

What about LBAs of negative trials that haven't had top-line releases stating that they are negative? Perifosine and bapi were both announced as negative before being presented. Don't get me wrong, I am not at all trying to insinuate that no news is good news re: PPHM and am frankly confused why the PPHMers are still being engaged as if they can be reasoned with at all, but in my limited experience, I can't think of a LBA that has been negative without having some sort of top-line release ahead.

I suppose it is probably different for company-sponsored vs. co-op group trials as well, but all the negative LBAs I can think of have been known to be negative before. Again, just want to reiterate that I am in no way suggesting this has any bearing on PPHM, but it did make me a little curious.