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genisi

05/21/12 11:30 AM

#142302 RE: urche #142295

Data suggest that genetic modulation of HDL doesn't affect the risk of MI. Still, our understanding of the whole picture is not complete. Some genes are not yet known, some complex interactions not fully understood and there are also surprising/confusing findings such as that at the HNF4A locus, the HDL raising allele is very much associated with increased risk of MI (p=0·0009).