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genisi

05/14/12 9:45 AM

#141874 RE: biotech jim #141873

Indeed the malignancies risk a real concern as it shows time-dependency pattern, but similar to what you've posted in #msg-75312624 I think RA docs want different drugs in the arsenal and they are familiar with immunosupressants side effects/risks and of course they will not put most patients on this drug.

kamehameha

05/14/12 9:53 AM

#141875 RE: biotech jim #141873

initially starting with non-selective agents and then getting more selective

that's why the JAK3 inhibitor VX-509 is a good bet!