PSMA ADC:
Well, there's not much there to sink our teeth into is there?
Off-hand I would not put much weight into PSA. I think you're of the same inclination.
As for the CTCs, I looked at the abstract and couldn't really see how they measure them. What is the marker they use to identify them? Do they sort them by FACS?
One of the things to be careful with these various "circulating" cells is that they're often very low in number, and the reproducibility of the measurement is therefore rather poor. I see a lot of this type of "circulating progenitor cell" type data around my area, and the numbers of cells identifiable is usually very low and, due to that, poorly reproducible. Without knowing what the magnitudes of those CTCs are, I wouldn't be too reliant on those data.
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