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iwfal

01/22/12 11:25 AM

#135465 RE: jq1234 #135463

CLDX

there is no point to look at the whole G+ population in ph1/2 as predicative for ph2b because ph2b include only significant G+ pts where majority will be triple negative.



I don't see the logic here - but I am not sure it matters unless you are saying that you expect the ORR in the treated group to be closer to 20% than 10%??? (I don't think you are, in fact, saying this - but because I don't understand your logic I am unsure.)