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exwannabe

01/21/12 5:24 PM

#135443 RE: mcbio #135440

CLDX:

... ORR was 22% in patients with "significant stromal or tumor cell expression of GPNMB." So, not sure where you get that ORR was unknown in these patients. ...



. In the entire trial there were 2 (N=33?) ORs.
. 14 were sampled for G+, 9 were positive
. Of those 9, 2 had CRRs (22%)

But what about those not tested? One would expect something like 10 G+ in those, and they had 0 ORs.

And I would assume that both ORs were intentionally included GPNMB sampling, so that the sampled subset is biased from the start.