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12/16/11 1:37 PM

#133188 RE: ghmm #133142

the MRK BACE program is indeed from Ligand. Phase 1 single dose showed the 58% reduction mentioned in LGND 10k, Phase 1 multidose showed 90% reduction (November 2011 MRK slides), and phase 2 to start 2012.

As is the case for numerous of their programs, Ligand knows nothing more than what MRK has put out publicly.