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biotech jim

12/13/11 9:28 PM

#133015 RE: DewDiligence #133004

On December 12, 2011, the Company's Board of Directors expanded the size of the Board from 13 to 15 members. In addition, the Board of Directors elected Dr. Marc Tessier-Lavigne and Dr. Helen Hobbs to serve as members of the Board, effective immediately.



Helen Hobbs is in Joe Goelstein's medical genetics department at UT Southwestern and discovered the non-enzymatic activity of PCSK9 in the regulation of cholesterol levels. She also described some patients with mutant PCSK9 and the consequent protective effects on cholesterol levels.