And even though the ratio is favorable at the current price, it is also important to size the bet correctly relative to one's portfolio.
Totally agree with that. I never hold less than 6 biotechs and I will go up to as many as 8 at any given time just because no matter how confident you are in the risk-reward of any given holding, biotech is wildly unpredictable and it pays to diversify. I also generally like to limit any individual holding to no more than 20% of my biofolio, but I am slightly breaking this personal rule with ARRY.