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oc631

11/05/11 2:12 PM

#130342 RE: DewDiligence #130339

Please clarify.





Considering the resistance profile of the nucleotide class it will be years before viral mutation requires an additional drug like DEB-025 in the first line setting. By that time the majority of patients in the developed world will have been treated and hopefully will have achieved a SVR. Misuse of the drug in the undeveloped world will lead to increased chances of viral mutation.