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oc631

11/05/11 1:50 PM

#130338 RE: DewDiligence #130336

Why would DEB025 have to be relegated to the second- or third-line setting? If it can add modest efficacy to a nuke-based regimen with no increase in resistance, I see no reason why DEB025 is unsuited to the first-line setting.





I agree with you its possible and I obviously am not being clear in my original statement. It could see first-line usage in future treatment if mutation within the nuke class became an issue. I don't see this as being a problem in the developed world.