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acgood

11/05/11 12:46 PM

#130321 RE: DewDiligence #130320

DEB025 is so different from other HCV drug candidates that we should expect the data reporting to deviate from the standard industry metrics to some degree



That may be the case...I have no idea. But that language is the sort of slippery slope to false claims and excuses that we would criticize other companies for deploying.
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oc631

11/05/11 12:57 PM

#130325 RE: DewDiligence #130320

Looking at alisporivir under current efficacy metrics makes this drug look quite underwhelming. Perhaps there's a slow building mechanism of action? The best drugs in the space knock the virus down below the LOD at 2-weeks with a 90%+ SVR rate.