November marks Pancreatic Cancer Awareness Month. According to the American Cancer Society, more than 44,000 new cases of pancreatic cancer will be diagnosed in the U.S. and over 37,000 deaths are expected from the disease in 2011. It has the highest mortality rate of all major cancers;...
Visibility for the disease is on the rise following the recent deaths of Apple, Inc. (AAPL) co-founder Steve Jobs and Ralph Steinman, a cell biologist who died several days before being named one of three winners for the 2011 Nobel Prize in Medicine. While awareness is increasing, there is an urgent need for more effective treatments and diagnostics to detect the disease earlier due to the fact that the number of new pancreatic cancer cases is projected to increase by 55% from 2010 to 2030[3].
Article by Michael Becker about a "Baker's Dozen" of treatments.
Any thoughts on the drugs listed or the author?
Table 1. Baker’s Dozen in Active Clinical Development for Pancreatic Cancer [modified slightly to fit here better. immuno = Immunotherapy chemo = chemotherapy]
Company Product Class [Clinical Trial] Stage Aduro BioTech, Inc. (private) Cancer Vaccines CRS-207 & GVAX Pancreas Immuno Ph II Amgen (AMGN) AMG 479 Immuno Ph II Celgene Corporation (CELG) Abraxane Chemo Ph III Celgene Corporation (CELG) & GlobeImmune (private) GI-4000 Immuno Ph II Clovis Oncology, Inc. (private) CO-101 Chemo Ph II Immunomedics (IMMU) 90Y-hPAM4 Radiopharmaceutical Ph Ib Infinity Pharmaceuticals (INFI) IPI-926 Signal transduction inhibitor Ph Ib/II NewLink Genetics Corporation (private) HyperAcute®-Pancreas (Algenpantucel-L) Immuno Ph III Novartis AG (NVS) & Bayer Schering Pharma AG (BAYRY.PK) Vatalanib (PTK787/ZK-222584) Kinase inhibitor Ph I/II Oncolytics Biotech (ONCY) Reolysin® Reovirus Ph II Pharmacyclics (PCYC) PCI-27483 Signal transduction inhibitor Ph II Seattle Genetic. (SGEN) & Astellas Pharma (ALPMY.PK) ASG-5ME Immuno – drug conjugate Ph I Threshold Pharmaceuticals (THLD) TH-302 Chemo Ph II