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NP1986

08/26/11 11:15 AM

#125690 RE: pcrutch #125688

Why are they comparing it against DTIC/TMZ when TMZ isn't even approved for this indication?



Until recently, there weren't many approved treatment options for melanoma. Pfizer's phase III tremelimumab trial used the investigator's choice of DTIC or TMZ as the comparator. I don't see much wrong with using TMZ as a comparator.

Nevertheless, I can't really comment on Allovectin-7 itself.

drbio45

08/26/11 7:42 PM

#125722 RE: pcrutch #125688

thank you

Someone asked me about it and you have given me a very thoughtful response.