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biomaven0

08/24/11 11:19 AM

#125585 RE: DewDiligence #125582

but not faster



I was comparing with skeletal events (presumably fractures) as an endpoint. I have no idea of what the rate of these is in late-stage populations is - conceivably of the same order as survival.

It's worth noting that the FDA has approved two drugs with pain reduction in prostate cancer as the primary endpoint - Mitoxantrone and Samarium. So that bolsters the notion that a combined pain/bone scan endpoint would be acceptable.

Peter