FCSC…there have been no significant safety issues.
You’re going around in circles. As noted in #msg-64138359, the advisory committee rejected laViv on safety, and there are always going to lingering worries about safety when a biologically active cell-based product is used for a cosmetic indication.
Using laViv to treat nasolabial folds is like using a blowtorch instead of a vacuum cleaner to get rid of cobwebs in your attic.