"Some patients develop reactions to iodine. They may experience skin irritation if povidone iodine is applied. Ingesting this compound is also not safe, and it is important to keep it out of reach of children and pets, although the flavor can be a significant deterrent to all but the most determined consumers. If someone does ingest povidone iodine, a poison control center should be called for treatment advice. Sometimes this product is used as a mouthwash, but patients are expected to spit it out after use."