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DewDiligence

05/28/11 3:23 PM

#120720 RE: masterlongevity #120708

In Elan's primary analysis, they used a linear model to measure benefit of Bapineuzumab over PBO, instead of calculating benefit on actual observed data.

I do not understand precisely what this means. Can you elaborate?
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genisi

05/29/11 12:06 PM

#120726 RE: masterlongevity #120708

One more concern I see about bapi phase II data is the lack of dose response related to efficacy* (in contrast to safety where vasogenic edema was dose-related).

*Both efficacy and vasogenic edema were related to ApoE4.