In all honesty, this is one of the reasons why I stay away from investing in diabetes, pain, and obesity drug companies. I just think a LOT of these trials have rule benders, and I just feel like there is always some sort of "kink" in the way the trial is designed, or the way the data is read, or something.
Just my observation. Perhaps I've just had some bad luck in the past and really don't understand those indications all that much. Or, perhaps not.