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manshoon1

04/09/11 6:47 PM

#16822 RE: igotthemojo #16820

once again, you dont know what kblb has...you think you know but you dont...you make it all sound so simple...just mutate the crap out of silk sworms and they will continue to produce and peform just like always, except what they produce will be completely changed or enhanced a thousand fold...

I gotta break this down soooo simple now. Silkworm A can make a silk used for the cocoon, the factories unravel the cocoon into a thread. Silkworm kblB, makes a thread, is uses this thread for its cocoon, factories will unravel this thread.....enhanced a thousand fold? The silkworm expresses a new protein, which currently nearly doubles the silk's tensile strength. They already have produced worms and unraveled the cocoons of those worms.

maybe so...but if were all that simple, wouldnt kblb already be done?...supposedly theres no fda to worry about and little restrictions so whats the delay?

First off, the life cycle is 30-60 days of the bombyx mori. 2nd, not all worms express the traits from the insertions, they have to screen to find the ones that do, test them etc... Homozygosis must be reached, which takes time to get commercial once a confirmed new strainn is achieved. FDA? has nothing to do with our current silks.

answer= its really not that simple and you really dont know if what you are saying is truly accurate...im sure its what you want to be true..

There is nothing simple about transgenesis. Talking about mechanical properties is simple though.

as far as the companies i mentioned, posters here have posted links to some companies that are also working on spidersilk and have recieved funding from various sources...you can go back and look or just google it...i cant imagine it would be that hard for you..

I was asking you, I do know of other companies/universities, but since you dont, you speak too broadly and clump them together. SOme are working on transgenic plants,goats,bacteria, and some silkworm.......

but notre dmae hasnt said much of anything...its kblb thats has been making all the claims

Simply an outright false statement.

heres an excerpt from that Wired Science article "I think it’s a big step forward,” said biomedical engineer David Kaplan of Tufts University. Until a scientific paper is published, he notes, there’s no way to know how important or useful the silk will prove. But “the principle is very nice,” he said. “I’m anxious to see more."

the guy is a biomedical engineer and in his impartial opinion, HE doesnt know that kblb has anything worthwhile or not..



Again your overgeneralized logic at work. Our current silk is targeting the ALREADY EXISTING SILK MARKET, what dont you get about that?

Only knowing that the silk is stronger, more flexible, thinner and smoother, is not enough to say it can be used for x application or y applicaiton. Common sense, for this silk to go commercial....the silk's properties would have to be shown and the silk itself would have to be shown with a suitor wanting to take our worms commercial.

The current silk won't compete in the technical textiles market, or with medical applications........so only you are surprised by this, we all knew this MANY MONTHS AGO.
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joecrabs

04/09/11 6:47 PM

#16823 RE: igotthemojo #16820

Impartial opinion?! You have just proven the worthlessness of the post. Kaplan has been spending decades researching silk and spider silks. Thank goodness he is so impartial to recognize that all his work may be for naught. Here's an excerpt on him:

Silk research spans a decade

Kaplan and his fellow researchers have been working on silks for more than a decade and have focused on these specific spider silk-silica chimeric proteins for about a year.

“We have worked on silks for a long time and we were designing new versions of silks using genetic engineering,” said Kaplan. “Since the diatom and other mineral forming domains had recently been identified in the literature, the silk-silica combination seemed potentially important from a materials perspective.”

In 2002, Kaplan and his team of researchers from Tufts’ School of Engineering and School of Medicine developed a tissue engineering strategy to repair one of the world’s most common knee injuries -- ruptured anterior cruciate ligaments (ACL) -- by mechanically and biologically engineering new ones using silk scaffolding for cell growth. A year later, Kaplan and a postdoctoral fellow at Tufts discovered how spiders and silkworms are able to spin webs and cocoons made of silk and aspects of the spinning process to replicate it artificially.

Source: Tufts University