Replies to post #114805 on Biotech Values

[DewDiligence]

The article referenced earlier states the SOC treatment of interferon and ribavarin works by boosting the immmune system, which is entirely false. As was explained to me pre-treatment, the interferon attacks the existing viral infection, and the ribavarin prevents the virus from replicating.

The article is correct, although these kinds of MoA characterizations should not be taken too literally. Interferon is considered an immunomodulator, not a direct-acting antiviral. Ribavirin is a DAA but it’s a weak one, and hence ribavirin’s contribution to the standard HCV regimen may be based in part on immunomodulation. Regards, Dew