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12/14/10 7:39 PM

#110916 RE: DewDiligence #110869

Re: NVS oncology webcast/ARRY

There were just a couple of references to MEK162/ARRY-162 during NVS' oncology webcast today.

1. Slide 39/41 minute mark: MEK162 will be used in multiple combinations with NVS' PI3K inhibitor program in the very near future.

2. Q&A/1:11 mark: By the end of 2011 there should be enough data to understand the activity of MEK162.