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jq1234

11/18/10 4:34 PM

#109218 RE: DewDiligence #109217

The Denosumab phase-3 trial due to report any day has progression-free survival as the primary endpoint.



It's Bone Metastasis-Free Survival. But patients enrolled in the trials couldn't have prior or current evidence of radiographically detectable bone metastasis, which is entirely different from EXEL184.

I don't know how else to convince you Denosumab and XL184 are NOT competing drugs.