Replies to post #108648 on Biotech Values

[dewophile]

Rib will be equally synergistic with DAA as it is with IFN. (Possible - but...)

i would have to think a company runs some preclinical data on DAA + rib prior to entering the clinic

[DewDiligence]

…but that is a weak "suggestion" of efficacy (to use their word).

VRTX’s PR could have been worded better, but the suggestion of ribavirin efficacy based on the results from its omission is what VRTX is banking on.

No one has conducted a trial in which HCV patients (as opposed to healthy volunteers) received a single DAA plus ribavirin without interferon for an extended period time; it would be insane to do so.