there is a very low float and i am sure there is plenty of manipulation going on. as i've said before, the downside risk is a few dollars on the stock price but the upside could easily be $15-$20+ upon approval. i don't believe there will be an outright rejection if not approved. i think it's worth the risk to hold at least some shares going into PDUFA. of course, never risk more than you can afford to lose.
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