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DewDiligence

09/19/10 8:31 PM

#104588 RE: rkrw #104584

The squamous won't kill them.

But see ifwal’s concern in #msg-53783981, which has not to my knowledge been dismissed.
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jq1234

09/19/10 9:08 PM

#104593 RE: rkrw #104584

What's more interesting to me is what drugs will be combined with PLX to extend the impressive but still relatively modest duration.



I heard discussion between Roche and BMY to combine PLX with Ipi.
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genisi

09/20/10 7:16 AM

#104600 RE: rkrw #104584

What's more interesting to me is what drugs will be combined with PLX to extend the impressive but still relatively modest duration.

And resistance (in addition to limited duration). GSK is running a combo trial of BRAF + MEK Inhibitors in melanoma to eliminate resistance.

http://clinicaltrials.gov/ct2/show/NCT01072175?term=GSK2118436++GSK1120212&rank=1