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DewDiligence

09/07/10 3:29 PM

#103650 RE: mcbio #103637

Did management say which of the two arms experienced the SAEs? I know the dosage of IDX184 and IDX320 were the same in both arms, but the treatment order was reversed in each arm.

The two SAE’s that are not explainable by the gallstone event were in the arm that had two weeks of IDX320 and one concurrent week of IDX184. The gallstone patient was in the arm that had two weeks of IDX184 and one week of concurrent IDX320.
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turtlepower

09/07/10 5:13 PM

#103662 RE: mcbio #103637

This may be good news for ACH-1625. Viral load reduction @ 400mg for 320 appears to be less than that for 1625 @ 500 mg and 600 mg.