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08/26/10 1:52 PM

#102625 RE: DewDiligence #102623

ZGEN -

What was going on between Oct 2009 and Jun 2010—the phase-2a portion of the trial?



Correct - the 2a portion was a dose ranging trial with various constant dosages (as opposed to a dosing per kg as was done in the ph 1) and dosing step downs (as is done for traditional ifn when liver enzymes go too high).