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Replies to #1724 on Entremed (ENMD)
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C_Peptide

02/01/05 10:10 PM

#1726 RE: cycle dude #1724

cycle_dude, the nanoparticles you have been citing are intravenous medicines that travel through the bloodstream as tiny particles to the target tissues. Panzem NCD is an oral medicine which is finely ground for the purpose of dissolving into the bloodstream faster than the intestinal enzymes can destroy it. Once dissolved, it is no longer a "particle", but an individual molecule.

It may be true that intravenous nanoparticles become preferentially taken up by the dysfunctional vasculature of malignant tumors, making them good vehicles for drug delivery. I hope it can be used to make existing and future drugs work better. However, the "N" in oral Panzem NCD does not refer to this application of nanoparticles any more than the "N" in Nuclear Magnetic Resonance Imaging involves splitting your atoms as a nuclear reactor would.

Best Regards,
C-Peptide