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Replies to #99260 on Biotech Values
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DewDiligence

07/22/10 9:55 AM

#99264 RE: mcbio #99260

Ok—I’ll add ACHN to the compilation. I may remove GILD since it no longer appears to be a serious contender.
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DewDiligence

08/11/10 10:43 PM

#101430 RE: mcbio #99260

Who’s Who in All-Oral HCV Programs

[Updates:
new entry for ACHN;
new entry for VRUS’ dual-nuke cocktail;
removed GILD’s program, which is dead in the water (#msg-52470566);
added clinicaltrials.gov link for IDX184+IDX320 DDI study.]


Protease Other Non-PI Dosing
Company Inhibitor Compound Class Frequency Link

VRTX Telaprevir VX-222 non-nuke BID http://clinicaltrials.gov/ct2/show/NCT01080222
Roche ITMN-191 RG7128 nuke TID/BID http://clinicaltrials.gov/ct2/show/NCT00801255
BMY BMS-650032 BMS-790052 NS5A BID http://clinicaltrials.gov/ct2/show/NCT01012895
B-I BI 201335 BI 207127 non-nuke TID/BID http://clinicaltrials.gov/ct2/show/NCT01132313
IDIX IDX320 IDX184 nuke qD† http://clinicaltrials.gov/ct2/show/NCT01157104
ACHN ACH-1625 ACH-2928 NS5A qD *
VRUS n/a PSI-7977 nuke/nuke qD *
+PSI-938

*All-oral trial has not started.
†BID for genotype-3 only.