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RULiquid

12/02/04 8:07 AM

#329170 RE: Zeev Hed #329168

NEW FLU TRACKER(PR NEWSWIRE) Americans Can Monitor U.S. Flu Rates on the First-Ever Desktop Fl
Tracker
Americans Can Monitor U.S. Flu Rates on the First-Ever Desktop Flu Tracker

Breakthrough Technology Makes Customized Flu Data Easily Accessible From Home
or Office Computer

NUTLEY, N.J., Dec. 2 /PRNewswire/ -- Roche announced the launch of its new
Desktop Flu Tracker, which allows users to conveniently and accurately track
the appearance and spread of flu in any community in the continental United
States. A valuable tool for consumers, medical professionals, caregivers and
public health officials, Flu Tracker allows people to monitor flu incidence in
their area, an important step in influenza preparedness.
Developed with AdTools Inc., the unique software application provides up-
to-date information about local and national flu levels 24 hours a day, seven
days a week. The Flu Tracker also alerts the user when there is an increased
risk in the area, and links directly to expert information on prevention and
treatment.
The Desktop Flu Tracker utilizes information from FluSTAR(TM) (System for
Tracking And Reporting Flu), a comprehensive surveillance system that provides
reliable reporting of flu activity nationwide, and is updated twice weekly.
The Desktop Flu Tracker can be downloaded at http://www.tamiflu.com or by
clicking here: http://www.tamiflu.com/flutracker.
"With this season's vaccine shortage, Americans are increasingly concerned
about protecting themselves and their families from the flu," said Dominick
Iacuzio, PhD, Medical Director, Roche, which markets Tamiflu, a prescription
antiviral for influenza. "Flu Tracker offers consumers and healthcare
providers alike an opportunity to identify flu outbreaks in their area, making
it more likely that patients will recognize their symptoms and seek early
treatment from a healthcare professional."
The Desktop Flu Tracker can be programmed to cover three geographic
locations, offering the ability to monitor for family and friends in other
areas. The software includes an animated character, which delivers alerts and
demonstrates the differences between cold and flu, so that users may better
understand their symptoms.
"FluTracker is designed to not only help individuals track flu, but also
to provide immediate access to expert information," added Dr. Iacuzio. "It
gives an opportunity to take extra precautions against infection, such as
visiting a doctor or taking an antiviral medication, which needs to happen
within the first 48 hours of symptom onset to be effective."
Unlike many desktop programs, the Flu Tracker is not bundled with any
additional programs and does not send personal information from the user's
desktop to any other computer.

About Tamiflu
Tamiflu is a prescription antiviral approved for the treatment of
influenza in patients one year and older. Tamiflu is an effective treatment,
and can reduce the duration and severity of the flu when taken within two days
of symptom onset. Tamiflu is also approved for the prevention of influenza in
adults and adolescents 13 years and older. Clinical trials have shown Tamiflu
to be up to 92 percent effective in preventing influenza illness when taken
once daily for at least seven days. Frequently reported adverse events
include nausea and vomiting.
Tamiflu, co-developed by Roche and Gilead Sciences, Inc., is a systemic
treatment for the most common strains of influenza (types A and B). The
medication targets one of the two major surface structures of the influenza
virus, the neuraminidase protein. The neuraminidase site is virtually the
same in the most common strains of influenza, types A and B. Tamiflu attacks
the influenza virus and is thought to work by stopping it from spreading
inside the body. Tamiflu treats flu at its source, by attacking the virus
that causes the flu, rather than simply masking symptoms.
Tamiflu is generally well tolerated. In treatment studies in adults, the
most frequently reported adverse events were mild-to-moderate transient nausea
and vomiting. Other events reported more frequently than with placebo were
bronchitis, insomnia and vertigo. In prophylaxis studies in patients aged 13
and older, adverse events were qualitatively similar to those seen in the
treatment studies despite a longer duration of dosing. Events reported more
frequently in subjects receiving Tamiflu compared to subjects receiving
placebo in prophylaxis studies included nausea, vomiting, diarrhea, abdominal
pain, dizziness, insomnia, headache, vertigo and fatigue.
In pediatric treatment studies, the most frequently reported adverse event
was vomiting. Other events reported more frequently by pediatric patients
treated with Tamiflu included abdominal pain, epistaxis, ear disorder and
conjunctivitis. These events generally occurred once and resolved despite
continued dosing.
Efficacy of Tamiflu in the treatment of subjects with chronic cardiac
disease and/or respiratory disease has not been established. Safety and
efficacy of repeated treatment or prophylaxis courses have not been studied.
Vaccination is considered the first line of defense against influenza.
Tamiflu was approved by the U.S. Food and Drug Administration (FDA) for
the treatment of uncomplicated acute illness due to influenza infection in
adults in October 1999. The FDA granted marketing approval for the prevention
of naturally occurring influenza A and B in adults and adolescents 13 years
and older in November 2000. The FDA granted marketing approval of the oral
suspension for use in the treatment of influenza A and B in children one year
and older in December 2000. Tamiflu oral suspension is used for pediatric
patients one year and older or adult patients who cannot swallow a capsule.
Tamiflu is the first and only liquid suspension to treat influenza A and B.
Tamiflu is available for the treatment of influenza in more than 40
countries worldwide. For more information visit http://www.Tamiflu.com

About Roche
Hoffmann-La Roche Inc. (Roche), based in Nutley, N.J., is the U.S.
prescription drug unit of the Roche Group, a leading research-based health
care enterprise that ranks among the world's leaders in pharmaceuticals and
diagnostics. Roche discovers, develops, manufactures and markets numerous
important prescription drugs that enhance people's health, well-being and
quality of life. Among the company's areas of therapeutic interest are:
dermatology; genitourinary disease; infectious diseases, including influenza;
inflammation, including arthritis; metabolic diseases, including obesity and
diabetes; neurology; oncology; osteoporosis; transplantation; vascular
diseases; and virology, including HIV/AIDS and hepatitis C. For more
information on the Roche pharmaceuticals business in the United States, visit
the company's web site at: http://www.rocheusa.com

About AdTools
AdTools employs its proprietary Desktop Marketing Communications
Technology platform to build turnkey internet-connected applications that
create a brand relationship directly on the desktop. AdTools has been building
desktop communicators, ScreenMate(TM) animated characters, alerts, advergames,
and groupware applications since 1997 for Fortune 500 and other major
companies in industries such as consumer products, travel and leisure, and
entertainment. More information is available at http://www.adtoolsinc.com.

SOURCE Roche
-0- 12/02/2004
/CONTACT: Sue Preziotti, +1-212-453-2144; or Megan Driscoll,
+1-212-453-2387, both for Fleishman-Hillard; or Terence Hurley of Roche,
+1-973-562-2882, or terence_j.hurley@roche.com /
/Web site: http://www.adtoolsinc.com
http://www.rocheusa.com
http://www.Tamiflu.com
http://www.tamiflu.com/flutracker /

CO: Roche; AdTools Inc.
ST: New Jersey
IN: CPR MLM HEA MTC
SU: PDT
*** end of story ***

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Public Heel

12/02/04 9:05 AM

#329206 RE: Zeev Hed #329168

If it's been wrong 86% of the time, then it's the best contrary indicator out there <g>. We could all make fortunes betting against it. (Not you, though, Zeev. I think betting against your own prediction violates some basic universal law)