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Replies to #4691 on Biotech Values
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urche

11/09/04 11:12 AM

#4692 RE: DewDiligence #4691

Thanks for the Accomplia study link from the AHA meeting. I gather from the little bit of digging I did that the results look good but we are told nothing about side effects. Of course, the implication is that side-effects were tolerable for a large number of people who completed a year on the drug. But, from what I have seen, the seemingly high incidence of nausea is the biggest red flag for this drug. Still sniffing for more data,
Urche
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Biowatch

11/09/04 7:13 PM

#4702 RE: DewDiligence #4691

Acomplia: 1 year vs 2 year data

http://news.yahoo.com/news?tmpl=story&u=/nm/20041105/hl_nm/health_sanofi_acomplia_dc_1

>>10 PERCENT WEIGHT LOSS

Results of two earlier studies have shown that around 40 percent of patients who stay on Acomplia for a year lose more than 10 percent of their body weight. The drug also boosts levels of "good" HDL cholesterol in the blood<<

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What's odd is that the earlier Reuters story says that "around" 40% of patients lost more than 10% of their body weight after one year, yet the story you quote says that only ("nearly") 33% of the patients on the drug for two years lost more than 10% of their body weight.

I also suspect that reporting the percentage of body weight lost may be better than measuring inches (or centimeters) lost around the waistline, especially if the latter isn't given as a percentage of the initial measurement.