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Replies to #86790 on Biotech Values
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DewDiligence

11/29/09 9:08 PM

#86792 RE: julescat #86790

HCV quiz answer:

How about Bristol-Myers Squibb with BMS 790052, an NS5A inhibitor, and BMS 650032, an NS3 inhibitor?

Bingo!
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DewDiligence

12/19/09 5:31 PM

#87816 RE: julescat #86790

Follow-up quiz on BMY’s all-oral HCV combo:

The following trial combines two oral HCV drugs from Bristol-Myers: BMS-650032, a protease/NS3 inhibitor, and BMS-790052, an NS5A inhibitor:

http://clinicaltrials.gov/ct2/show/NCT01012895

This study was the answer to a recent quiz solved by ‘julescat’ (#msg-44002107, #msg-44000662). It’s the only HCV study (as far as I know) where two oral agents—of which neither has completed even a phase-2a study—are being combined in a regimen that does not include interferon or ribavirin.

New quiz question: What other consequential feature of this trial is a first in the HCV arena?