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entdoc

11/04/09 10:37 AM

#44160 RE: asmarterwookie #44158

wook,sumpin'like that. You're right, we've known for some time that Bavi "upregulates" immune response. Don't think we knew it might help confer immunity to re-challenge (2nd set phenomenon?). However, we should remember that the phenom. was presumably only seen in 13%...the survivors. That presupposes a "subset" of test subjects [rats], or some other undetermined variable in the 13%.
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co3aii

11/04/09 11:12 AM

#44166 RE: asmarterwookie #44158

asmartwookie, is this the part you referred to?

"Second, the antibody treatment induced immunity to F98 tumor cells, which are normally weakly immunogenic. Surviving rats were immune to rechallenge with F98 tumor cells."

In effect a vaccine?