Replies to post #85650 on Biotech Values

[iwfal]

If I remember correctly only 1 of 60 patients treated with 2042 had microdeposits after 3 months of treatment whereas 80-90% of amiodarone patients had microdeposits after 3 months of treatment.

That's true - but if I had to list the amiodarone SAE in importance (reason for halting drug) I'd list them as:

thyroid
liver
QTc
...
corneal deposits

And the presentation of Budiodarone ph iib data shows that the first 2 are still there. Maybe at a lesser rate, maybe not. Hard to tell in a trial with 15 patients per arm - and where the details of the Amiodarone blood marker data are hard to come by.

Also note that, like D, (and unlike A?) it is likely to cause a renal problem because of creatinine.