I know, I know. I really wish more patients would take control of their health care. Very little of this is really brain surgery, only a tiny fraction involves opening up the the calvaria and poking around in there. A doc sees a patient for 15 minutes a year maybe, a patient lives in their body for 24/7/365. Who knows more, and who cares more.
That being said, I will mention one of my big pharma gripes. Drugs have become harder to find, common knowledge. So the big pharma solution is cannibalism, buying mid level or mini-mega pharms. So how sustainable is this?
You have 50 people on a deserted island with little food. They resort to cannibalism. Eventually you have one, presumably slightly batttered, survivor, and 49 piles of bones. Then what? This is the big pharma space in the 21st century. To my mind, this is a stop gap before they figure out something new or just the beginning of the end. I rather suspect the latter. A recent article in a trade publication was titled, "The end of the blockbuster drug." I really don't see many billion dollar drugs left to discover with present technology. Recent drugs are more focused and increasingly are used in combos.
This is good for the medicine but not necessarily for the drug companies.