Amiodarone is not approved for AF by the FDA but it is the most commonly used drug (especially in patients with left ventricular hypertrophy, because of its potency (why do you suppose they bothered doing a head-to head Multaq vs Amiodarone trial?). In fact, it is so effective that I doubt it will be matched by any of the newer agents. But it has a lot of side effects that limit its potential and make Multaq a safer choice.
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