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Replies to #79070 on Biotech Values
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DewDiligence

06/04/09 6:23 PM

#79076 RE: mcbio #79070

DVAX has an HCV vaccine in Phase 1 that's a TLR9 agonist… Perhaps they're the next batter up? Remember, 3 outs in an inning Dew : )

Actually, you can have four outs in an inning: if the catcher drops the ball on strike three and first base is open, the batter can run to first and try to beat the throw. The pitcher still gets credit for a strikeout even if the batter gets to first base safely. It’s a fluke play, but the outcome of one World Series hinged on such a play.

The odds on DVAX’s HCV vaccine being successful are probably about as long as the dropped-third-strike parlay :- )
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DewDiligence

07/20/11 11:16 PM

#123694 RE: mcbio #79070

IDRA—Here we go again with TLR-targeted drugs…

http://finance.yahoo.com/news/Idera-Reports-Clinical-Hold-bw-3688989363.html?x=0&.v=1

…a proposed Phase 2 protocol that the Company had recently submitted under an Investigational New Drug Application for IMO-3100 will be placed on a clinical hold. The proposed Phase 2 trial of IMO-3100 is for the treatment of psoriasis… IMO-3100, an antagonist of TLR7 and TLR9, is a lead clinical candidate in development to treat autoimmune and inflammatory diseases.