What's your take on this Dew? It looks like a survival advantage for TNFerade between 10 and close to 25 months but that all disappears and actually switches to an advantage for SoC post 25 months if I'm reading that right. That can't be good for TNFerade's prospects.
Those curves look better than what I had imagined in my head. But I agree with you that it is not the best idea to jump in before the second look.
This is somewhat tangential, but does anybody think they suffered from doing the uneven randomization in this trial? It looks to me like the control arm is pretty jumpy in the 5-10 month range, and I wonder if that is partly due to the smaller numbers in this arm? If larger numbers on the control arm could "smooth out" the K-M profile, they could have had a nice clear separation starting from 3 months and lasting well into 20 months.
I don't know if that's just wishful thinking or what..
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