didn't vertex show RVR without Rib doesn't translate to SVR?
Yes—the entire HCV industry is now of the opinion that, absent a newfangled combo of multiple direct antivirals, ribavirin has to remain in the cocktail.
Moreover, you can’t even skimp on the ribavirin dose to improve tolerability. SGP tried this in one arm of the Boceprevir SPRINT-1 study and it failed miserably.