News Focus
News Focus
Replies to #75545 on Biotech Values
icon url

iwfal

04/06/09 11:35 AM

#75546 RE: tony111 #75545

Does it concern you that Zymo is enrolling another cohort at 0.5mg ? I do hope its a sign that interferon lambda is too potent so its difficult to access the minimum effective dose :)



I would expect Zymo to not(!) skip a step like finding the entire therapeutic window.
icon url

dewophile

04/06/09 12:25 PM

#75550 RE: tony111 #75545

they are also enrolling a 3 mic per kilo dose, so it's not raising alarms for me, rather i think it is really just to flesh the dose response curve, particularly given its going to be part of a multidrug cocktail where cumulative toxicity becomes an important issue