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Replies to #71150 on Biotech Values
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DewDiligence

01/09/09 4:40 AM

#71158 RE: mcbio #71150

Prevalence of HCV genotypes in US:

Genotype-1a and -1b represent 57% and 17%, respectively, of the US pool of individuals with chronic HCV.

Source:
http://www.ncbi.nlm.nih.gov/pubmed/10451460
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genisi

01/09/09 6:57 AM

#71162 RE: mcbio #71150

In regards to HCV genotypes, it has been suggested that genotype 1, particularly 1b, does not respond to therapy as well as other genotypes and is associated with a more severe disease progression, but larger prospective clinical trials are needed to confirm this.


http://www.hcvadvocate.org/hepatitis/factsheets_pdf/genotype_2008.pdf

http://emedicine.medscape.com/article/177792-overview