<<Latisse will easily outsell Lumigan, which does about $500M annually...>>
I know a number of female glaucoma patients who have switched from Lumigan to alternatives because of darkening of the eyelids. If this is a concern where your vision is involved, I would guess it would be more of a concern where the drug is being taken for purely cosmetic reasons. This side effect is well-known -- google "+lumigan +"raccoon eyes"".